And now another disease with a microbial cause. Not MAP this time, but it makes you think!

“We are saying there is incontrovertible evidence that Alzheimer’s Disease has a dormant microbial component, and that this can be woken up by iron dysregulation. Removing this iron will slow down or prevent cognitive degeneration – we can’t keep ignoring all of the evidence,” Professor Douglas Kell said.

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March 2016

OK, call us geeky, but some of us at Crohn’s Map Vaccine are really into the science of bacteria, even though this has not been our background. We can thank the onset of Crohn’s in ourselves or a loved one for this enforced interest. For those of you who share our passion, here is an article (quite long, so be prepared) by Raffi Khatchadourian on the tantalising subject of microbial dark matter!

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June 2016

This is an excellent article from New Scientist about the accidental benefits of vaccines and makes a useful contribution to the immune system debate.
“If infections can alter the immunological milieu, it is not a major leap to suggest that vaccines might also do so,” said Andrew Pollard, head of the Oxford Vaccine Centre at the University of Oxford.

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August 2013

What if the cause of breast cancer also turns out to be mycobacterial for some women?

“[The results] suggest that microbes in the breast, even in low amounts, may be playing a role in breast cancer—increasing the risk in some cases and decreasing the risk in other cases,” says Gregor Reid, a professor of microbiology and immunology at Western University in Ontario and the study’s senior author.

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October 2016

“Blood has always been considered free from microbes, because bacteria don’t grow when it is put in a culture dish. But recent DNA sequencing methods reveal that each millilitre of blood in fact contains around 1000 bacterial cells..

These bacteria are usually dormant. But they can be revived when iron becomes available in the blood, and….. stimulate inflammation. Further research could open up several new approaches for tackling them, from removing dormant microbes from our blood, to blocking the inflammatory proteins that they shed.”

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September 2016