Conclusions: “These results are consistent with the notion that MAP are circulating in the peripheral blood of patients with Crohn’s disease either at low level or intermittently. Carefully designed clinical trials in Crohn’s patients that specifically confirm the presence of MAP and relate the responses to treatment and recurrence are required to establish a causal zoonotic link between the pathogen, a major food industry and a devastating chronic human gastrointestinal illness.”

http://metcorner.gastro.org/article/S0016-5085(17)33383-8/abstract