“The results of the survey and recent case reports of patients infected with MAP presenting with the clinical features of JD in cattle and CD in humans clearly show that MAP is a zoonotic pathogen.”

“A vaccine is needed to clear MAP from livestock and thereby the food stream. Antibiotic and other therapies are needed to treat humans infected with MAP who develop clinical disease.”

In this Feb 2017 paper Dr William Davis advocates a large trial of anti-MAP antibiotics on patients who are clearly infected with MAP, acknowledging that many of the parameters of the trial would necessarily overlap with those of the current RedHill trial, but that the proposed trial would afford the opportunity to fully evaluate current antibiotics and antibiotics under development.

http://www.tandfonline.com/doi/pdf/10.1080/17474124.2017.1300529